If this sign appears in your ear, it is a war:ning sign that you have ca…

 

1. What is Frank’s Sign?

Frank’s Sign refers to a diagonal crease running at roughly a 45° angle across the earlobe, also known as the diagonal earlobe crease (DELC). It was first described by Dr. Sanders T. Frank, who spotted this crease in 20 patients with angina.

Initially connected to coronary artery disease, later research has found the same crease present in patients with peripheral vascular disease and cerebrovascular disease as well. Essentially, the earlobe crease may be an external marker of poor bl00d circulation including in the coronary arteries rather than just a sign of aging.

2. Who commonly shows Frank’s Sign?

It is often followed in patients attending cardiology clinics, particularly those with a history of coronary artery bypass surgery. However, the presence of this crease in otherwise healthy individuals also suggests increased risk of vascular disease. Interestingly, the sign does not correlate with body weight because it can appear in both slim and overweight people.

3. Possible mechanisms behind Frank’s Sign

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